| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TRIM32/BBS11 |
| Specificity: |
This antibody reacts specifically with TRIM32/BBS11 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse TRIM32 |
| Gene ID: |
22954 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM), TRIM32, TRIM32 has six C-terminal NHL domains, TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), The TRIM32 gene encodes an E3 ubiquitin ligase, UbcH5c and UbcH6, a RING-finger and a coiled-coil motif, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, an autosomal recessive disorder characterized by pigmentary retinopathy, contains a domain structure composed of a B-box, hypogenitalism, it is expressed mainly in the skeletal muscle, learning disabilities and obesity, like all TRIM proteins, polydactyly, renal abnormalities, Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HT2A TATIP BBS11 |
| Also known as: |
TRIM32/BBS11 Polyclonal Antibody |
| Other name: |
Anti-TRIM32/BBS11 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TRIM32/BBS11 |
| Short name: |
Anti-TRIM32/BBS11 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TRIM32/BBS11 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
16380 |
| Gene: |
TRIM32 |
More about : TRIM32 |
| Long gene name: |
tripartite motif containing 32 |
| Synonyms gene: |
LGMD2H |
| Synonyms gene name: |
limb girdle muscular dystrophy 2H (autosomal recessive) tripartite motif-containing 32 |
| Locus: |
9q33, 1 |
| Discovery year: |
2001-08-10 |
| GenBank acession: |
U18543 |
| Entrez gene record: |
22954 |
| Pubmed identfication: |
11331580 7778269 16606853 |
| RefSeq identity: |
NM_012210 |
| Classification: |
Tripartite motif containing Ring finger proteins Bardet-Biedl syndrome associated |
| Havana BLAST/BLAT: |
OTTHUMG00000021026 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_211 |