| Long name: |
Biotin Conjugated, TRIM32/BBS11 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRIM32/BBS11 |
| Specificity: |
This is a highly specific antibody against TRIM32/BBS11 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse TRIM32 |
| Gene ID number: |
22954 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Additionally, Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM), TRIM32, TRIM32 has six C-terminal NHL domains, TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), The TRIM32 gene encodes an E3 ubiquitin ligase, UbcH5c and UbcH6, a RING-finger and a coiled-coil motif, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, an autosomal recessive disorder characterized by pigmentary retinopathy, contains a domain structure composed of a B-box, hypogenitalism, it is expressed mainly in the skeletal muscle, learning disabilities and obesity, like all TRIM proteins, polydactyly, renal abnormalities, Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
HT2A TATIP BBS11 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRIM32/BBS11 Conjugated |
| Short name: |
Conjugated, TRIM32/BBS11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, TRIM32/BBS11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16380 |
| Gene: |
TRIM32 |
More about : TRIM32 |
| Long gene name: |
tripartite motif containing 32 |
| Synonyms gene: |
LGMD2H |
| Synonyms gene name: |
limb girdle muscular dystrophy 2H (autosomal recessive) tripartite motif-containing 32 |
| Locus: |
9q33, 1 |
| Discovery year: |
2001-08-10 |
| GenBank acession: |
U18543 |
| Entrez gene record: |
22954 |
| Pubmed identfication: |
11331580 7778269 16606853 |
| RefSeq identity: |
NM_012210 |
| Classification: |
Tripartite motif containing Ring finger proteins Bardet-Biedl syndrome associated |
| Havana BLAST/BLAT: |
OTTHUMG00000021026 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_211 |