| Long name: |
Biotin Conjugated, AMACR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AMACR |
| Specificity: |
This is a highly specific antibody against AMACR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse AMACR |
| Gene ID number: |
23600 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AMACR is consistently overexpressed in prostate cancer epithelium, Furthermore, However PSA has limited specificity because benign disease, One such potential marker is AMACR, Recent studies have shown that, Thus, a more specific prostate cancer markers is needed, an enzyme that is involved in peroxisomal beta-oxidation of dietary branched-chain fatty acids, can increase PSA levels, compared with expression in normal or benign prostate epithelium, including prostatic enlargement and inflammation, making it a specific marker for cancer cells within the prostate gland, overexpression of AMACR may increase the risk of prostate cancer because its expression is increased in premalignant lesions (prostatic intraepithelial neoplasia), alpha-methylacyl-CoA racemase(AMACR/P504S) is Prostate-specific antigen (PSA) screening for prostate cancer is now widespread in the United States among men of all ages |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
RACE P504S |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AMACR Conjugated |
| Short name: |
Conjugated, AMACR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, AMACR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
451 |
| Gene: |
AMACR |
More about : AMACR |
| Long gene name: |
alpha-methylacyl-CoA racemase |
| Locus: |
5p13, 2 |
| Discovery year: |
1999-10-19 |
| GenBank acession: |
AF047020 |
| Entrez gene record: |
23600 |
| Pubmed identfication: |
9307041 |
| RefSeq identity: |
NM_014324 |
| Havana BLAST/BLAT: |
OTTHUMG00000090734 |