| Long name: |
AMACR Primary Polyclonal Antibody |
| Also known as: |
AMACR PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
AMACR |
| Specificity: |
This is a highly specific antibody against AMACR |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse AMACR |
| Gene ID number: |
23600 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AMACR is consistently overexpressed in prostate cancer epithelium, Furthermore, However PSA has limited specificity because benign disease, One such potential marker is AMACR, Recent studies have shown that, Thus, a more specific prostate cancer markers is needed, an enzyme that is involved in peroxisomal beta-oxidation of dietary branched-chain fatty acids, can increase PSA levels, compared with expression in normal or benign prostate epithelium, including prostatic enlargement and inflammation, making it a specific marker for cancer cells within the prostate gland, overexpression of AMACR may increase the risk of prostate cancer because its expression is increased in premalignant lesions (prostatic intraepithelial neoplasia), alpha-methylacyl-CoA racemase(AMACR/P504S) is Prostate-specific antigen (PSA) screening for prostate cancer is now widespread in the United States among men of all ages |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
2 arylpropionyl CoA epimerase, 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, AMACR, AMACR deficiency, AMACR_HUMAN, Alpha methylacyl CoA racemase, Alpha methylacyl Coenzyme A racemase, Alpha methylacyl-CoA racemase deficiency, Alpha-methylacyl-CoA racemase, Amacr, CBAS4, Da1-8, EC 5, Macr 1, Macr1, Methylacyl CoA racemase alpha, P504S, P504S, RACE, RACE, RM, alpha-methylacyl-CoA racemase isoform 1, included, included, 1, 2 arylpropionyl CoA epimerase, 4, 99 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AMACR |
| Short name: |
AMACR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AMACR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
451 |
| Gene: |
AMACR |
More about : AMACR |
| Long gene name: |
alpha-methylacyl-CoA racemase |
| Synonyms: |
RACE P504S |
| Locus: |
5p13, 2 |
| Discovery year: |
1999-10-19 |
| GenBank acession: |
AF047020 |
| Entrez gene record: |
23600 |
| Pubmed identfication: |
9307041 |
| RefSeq identity: |
NM_014324 |
| Havana BLAST/BLAT: |
OTTHUMG00000090734 |