| Long name: |
FITC Conjugated, AMACR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AMACR |
| Specificity: |
This is a highly specific antibody against AMACR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse AMACR |
| Gene ID number: |
23600 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AMACR is consistently overexpressed in prostate cancer epithelium, Furthermore, However PSA has limited specificity because benign disease, One such potential marker is AMACR, Recent studies have shown that, Thus, a more specific prostate cancer markers is needed, an enzyme that is involved in peroxisomal beta-oxidation of dietary branched-chain fatty acids, can increase PSA levels, compared with expression in normal or benign prostate epithelium, including prostatic enlargement and inflammation, making it a specific marker for cancer cells within the prostate gland, overexpression of AMACR may increase the risk of prostate cancer because its expression is increased in premalignant lesions (prostatic intraepithelial neoplasia), alpha-methylacyl-CoA racemase(AMACR/P504S) is Prostate-specific antigen (PSA) screening for prostate cancer is now widespread in the United States among men of all ages |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
RACE P504S |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AMACR Conjugated |
| Short name: |
FITC Conjugated, AMACR Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, AMACR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
451 |
| Gene: |
AMACR |
More about : AMACR |
| Long gene name: |
alpha-methylacyl-CoA racemase |
| Locus: |
5p13, 2 |
| Discovery year: |
1999-10-19 |
| GenBank acession: |
AF047020 |
| Entrez gene record: |
23600 |
| Pubmed identfication: |
9307041 |
| RefSeq identity: |
NM_014324 |
| Havana BLAST/BLAT: |
OTTHUMG00000090734 |