| Long name: |
FITC Conjugated, SYVN1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SYVN1 |
| Specificity: |
This is a highly specific antibody against SYVN1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
570-610/617 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human SYVN1 |
| Gene ID number: |
84447 |
| Swiss Prot: |
Q86TM6 |
| Tested applications: |
IF(IHC-F), IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also promotes the degradation of normal but naturally short-lived proteins such as SGK, Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins, Protects cells from ER stress-induced apoptosis, Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation, Sequesters p53/TP53 in the cytoplasm and promotes its degradation, cell cycle regulation and apoptosis, promoting their degradation, thereby negatively regulating its biological function in transcription, Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HRD1 DER3 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SYVN1 Conjugated |
| Short name: |
FITC Conjugated, SYVN1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, synoviolin (Antibody to), synovial apoptosis inhibitor 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, SYVN1 and IDBG-56611 and ENSG00000162298 and 102465449, Syvn1 and IDBG-134090 and ENSMUSG00000024807 and 74126, metal ion binding, nuclei, synoviolin, this GO :0001701 and in utero embryonic development and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016881 and acid-amino acid ligase activity and molecular function this GO :0018279 and protein N-linked glycosylation via asparagine and biological process this GO :0030433 and ER-associated ubiquitin-dependent protein catabolic process and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :1902236 and negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016881 : acid-amino acid ligase activity and also this GO :0046872 : metal ion binding, this GO :0008270 : zinc ion binding, this GO :0016881 : acid-amino acid ligase activity, this GO :0046872 : metal ion binding, 54995 and IDBG-644142 and ENSBTAG00000005076 and 508358, 84447, synovial apoptosis inhibitor 1 |
| Identity: |
20738 |
| Gene: |
SYVN1 |
More about : SYVN1 |
| Long gene name: |
synoviolin 1 |
| Synonyms gene name: |
synovial apoptosis inhibitor 1, synoviolin |
| Synonyms name: |
HMG-coA reductase degradation 1 homolog (S, cerevisiae) |
| Locus: |
11q13, 1 |
| Discovery year: |
2004-07-28 |
| GenBank acession: |
AB085847 |
| Entrez gene record: |
84447 |
| Pubmed identfication: |
12975321 |
| RefSeq identity: |
NM_032431 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000165607 |