p19ARF Antibody, ALEXA FLUOR 647

Catalog number:	bs-0534R-A647 Buy Now
Price:	Ask price €
Supplier:	accurate-monoclonals
Product name:	p19ARF Antibody, ALEXA FLUOR 647
Quantity:	1 vial
Related search:	alexa parf antibody gene this alternative blocks

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Long name:	ALEXA FLUOR 647 Conjugated, p19ARF Polyclonal Antibody
Also known as:	Anti-p19ARF PAb ALEXA FLUOR 647
Category:	Conjugated Primary Antibodies
Conjugated with:	647, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	p19ARF
Specificity:	This is a highly specific antibody against p19ARF
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P19ARF
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Rat, Mouse
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Acts as a tumor suppressor, Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes, Binds to BCL6 and down-regulates BCL6-induced transcriptional repression, Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression, Binds to HUWE1 and represses its ubiquitin ligase activity, Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus, Binds to TOP1/TOPOI and stimulates its activity, Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1, May play a role in controlling cell proliferation and apoptosis during mammary gland development, This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation, This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis, thus inhibiting rRNA processing, P19ARF Capable of inducing cell cycle arrest in G1 and G2 phases
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	650nm/665nm
Synonyms:	CDK4I p16 INK4a MTS1 CMM2 ARF p19 p14 INK4 p16INK4a p19Arf p14ARF
Properties:	ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the p19ARF Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 647, Alexa Fluor
Gene target:	p19ARF
Short name:	p19ARF Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 647
Alternative name:	ALEXA FLUOR 647, p19ARF (Antibody to)
Alternative technique:	antibodies
Identity:	1787
Gene:	CDKN2A | More about : CDKN2A
Long gene name:	cyclin dependent kinase inhibitor 2A
Synonyms gene:	CDKN2 MLM
Synonyms gene name:	cyclin-dependent kinase inhibitor 2A (melanoma, inhibits CDK4) , p16
Locus:	9p21, 3
Discovery year:	1994-05-19
GenBank acession:	L27211
Entrez gene record:	1029
Pubmed identfication:	8152487 7606716
RefSeq identity:	NM_000077
Havana BLAST/BLAT:	OTTHUMG00000019686
Locus Specific Databases:	LOVD - Leiden Open Variation Database LRG_11

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