| Long name: |
Cy7 Conjugated, PBEF1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PBEF1 |
| Specificity: |
This is a highly specific antibody against PBEF1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
290-340/491 |
| Subcellular location: |
Nucleus, Secreted, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human PBEF |
| Gene ID number: |
10135 |
| Swiss Prot: |
P43490 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It is the rate limiting component in the mammalian NAD biosynthesis pathway, NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity), Plays a role in the modulation of circadian clock function, The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, an intermediate in the biosynthesis of NAD, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma, Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
PBEF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
PBEF1 Conjugated |
| Short name: |
Conjugated, PBEF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, PBEF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30092 |
| Gene: |
NAMPT |
More about : NAMPT |
| Long gene name: |
nicotinamide phosphoribosyltransferase |
| Synonyms gene: |
PBEF1 |
| Synonyms gene name: |
pre-B-cell colony enhancing factor 1 |
| Synonyms name: |
visfatin |
| Locus: |
7q22, 3 |
| Discovery year: |
2004-02-02 |
| GenBank acession: |
U02020 |
| Entrez gene record: |
10135 |
| Pubmed identfication: |
8289818 |
| RefSeq identity: |
NM_182790 |
| Havana BLAST/BLAT: |
OTTHUMG00000140388 |