| Long name: |
ALEXA FLUOR 647 Conjugated, PBEF1 Polyclonal Antibody |
| Also known as: |
Anti-PBEF1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PBEF1 |
| Specificity: |
This is a highly specific antibody against PBEF1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
290-340/491 |
| Subcellular location: |
Nucleus, Secreted, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PBEF |
| Gene ID Number: |
10135 |
| Swiss Prot: |
P43490 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It is the rate limiting component in the mammalian NAD biosynthesis pathway, NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity), Plays a role in the modulation of circadian clock function, The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, an intermediate in the biosynthesis of NAD, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma, Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PBEF |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PBEF1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
PBEF1 |
| Short name: |
PBEF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, PBEF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30092 |
| Gene: |
NAMPT |
More about : NAMPT |
| Long gene name: |
nicotinamide phosphoribosyltransferase |
| Synonyms gene: |
PBEF1 |
| Synonyms gene name: |
pre-B-cell colony enhancing factor 1 |
| Synonyms name: |
visfatin |
| Locus: |
7q22, 3 |
| Discovery year: |
2004-02-02 |
| GenBank acession: |
U02020 |
| Entrez gene record: |
10135 |
| Pubmed identfication: |
8289818 |
| RefSeq identity: |
NM_182790 |
| Havana BLAST/BLAT: |
OTTHUMG00000140388 |