| Long name: |
PBEF1 Primary Polyclonal Antibody |
| Also known as: |
PBEF1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PBEF1 |
| Specificity: |
This is a highly specific antibody against PBEF1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
290-340/491 |
| Subcellular location: |
Nucleus, Secreted, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PBEF |
| Gene ID number: |
10135 |
| Swiss Prot: |
P43490 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is the rate limiting component in the mammalian NAD biosynthesis pathway, NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity), Plays a role in the modulation of circadian clock function, The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, an intermediate in the biosynthesis of NAD, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma, Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
1110035O14Rik, NAmPRTase, Nampt, Nicotinamide phosphoribosyltransferase, PBEF, PBEF1, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1, VISFATIN, VF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PBEF1 |
| Short name: |
PBEF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PBEF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30092 |
| Gene: |
NAMPT |
More about : NAMPT |
| Long gene name: |
nicotinamide phosphoribosyltransferase |
| Synonyms gene: |
PBEF1 |
| Synonyms gene name: |
pre-B-cell colony enhancing factor 1 |
| Synonyms: |
PBEF |
| Synonyms name: |
visfatin |
| Locus: |
7q22, 3 |
| Discovery year: |
2004-02-02 |
| GenBank acession: |
U02020 |
| Entrez gene record: |
10135 |
| Pubmed identfication: |
8289818 |
| RefSeq identity: |
NM_182790 |
| Havana BLAST/BLAT: |
OTTHUMG00000140388 |