| Long name: |
ALEXA FLUOR 594 Conjugated, AIF Polyclonal Antibody |
| Also known as: |
Anti-AIF PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AIF |
| Specificity: |
This is a highly specific antibody against AIF |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
130-180/613 |
| Subcellular location: |
Mitochondrion, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AIF |
| Gene ID Number: |
9131 |
| Swiss Prot: |
O95831 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Pig, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binds to DNA in a sequence-independent manner, In contrast, In response to apoptotic stimuli, Interacts with EIF3G, Plays a critical role in caspase-independent, The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i, and activates casapse-7 to amplify apoptosis, caspase-independent fragmentation of chromosomal DNA, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, pyknotic cell death in hydrogen peroxide-exposed cells, where it functions as a proapoptotic factor in a caspase-independent pathway, Functions both as NADH oxidoreductase and as regulator of apoptosis, and thereby inhibits the EIF3 machinery and protein synthesis, e |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AIF CMTX4 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
AIF |
| Short name: |
AIF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, AIF (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8768 |
| Gene: |
AIFM1 |
More about : AIFM1 |
| Long gene name: |
apoptosis inducing factor mitochondria associated 1 |
| Synonyms gene: |
PDCD8 NAMSD |
| Synonyms gene name: |
1 apoptosis inducing factor, axonal, mitochondria associated 1 , mitochondrion-associated, motor-sensory with deafness and mental retardation (Cowchock syndrome) apoptosis-inducing factor, programmed cell death 8 (apoptosis-inducing factor) neuropathy |
| Locus: |
Xq26, 1 |
| Discovery year: |
1999-05-28 |
| GenBank acession: |
AF100928 |
| Entrez gene record: |
9131 |
| Pubmed identfication: |
9989411 23217327 |
| Havana BLAST/BLAT: |
OTTHUMG00000022392 |
| Locus Specific Databases: |
Mental Retardation database |