| Long name: |
Cy3 Conjugated, AIF Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AIF |
| Specificity: |
This is a highly specific antibody against AIF |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
130-180/613 |
| Subcellular location: |
Mitochondrion, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human AIF |
| Gene ID number: |
9131 |
| Swiss Prot: |
O95831 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Pig, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds to DNA in a sequence-independent manner, In contrast, In response to apoptotic stimuli, Interacts with EIF3G, Plays a critical role in caspase-independent, The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i, and activates casapse-7 to amplify apoptosis, caspase-independent fragmentation of chromosomal DNA, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, pyknotic cell death in hydrogen peroxide-exposed cells, where it functions as a proapoptotic factor in a caspase-independent pathway, Functions both as NADH oxidoreductase and as regulator of apoptosis, and thereby inhibits the EIF3 machinery and protein synthesis, e |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
AIF CMTX4 |
| Properties: |
1 of the AIF Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AIF Conjugated |
| Short name: |
Conjugated, AIF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, AIF (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8768 |
| Gene: |
AIFM1 |
More about : AIFM1 |
| Long gene name: |
apoptosis inducing factor mitochondria associated 1 |
| Synonyms gene: |
PDCD8 NAMSD |
| Synonyms gene name: |
1 apoptosis inducing factor, axonal, mitochondria associated 1 , mitochondrion-associated, motor-sensory with deafness and mental retardation (Cowchock syndrome) apoptosis-inducing factor, programmed cell death 8 (apoptosis-inducing factor) neuropathy |
| Locus: |
Xq26, 1 |
| Discovery year: |
1999-05-28 |
| GenBank acession: |
AF100928 |
| Entrez gene record: |
9131 |
| Pubmed identfication: |
9989411 23217327 |
| Havana BLAST/BLAT: |
OTTHUMG00000022392 |
| Locus Specific Databases: |
Mental Retardation database |