| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Mouse (Mus musculus) |
| Target Protein/Peptide: |
AIF |
| Specificity: |
This antibody reacts specifically with AIF |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AIF |
| Gene ID: |
9131 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rabbit, Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A related pseudogene has been identified on chromosome 10, Alternative splicing results in multiple transcript variants, In addition, Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation, May 2010], Mutations in this gene cause combined oxidative phosphorylation deficiency 6, [provided by RefSeq, and it is found in the mitochondrial intermembrane space in healthy cells, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9, which results in a severe mitochondrial encephalomyopathy, This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AIF CMTX4 |
| Also known as: |
AIF Polyclonal Antibody |
| Other name: |
Anti-AIF Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AIF |
| Short name: |
Anti-AIF (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-AIF (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8768 |
| Gene: |
AIFM1 |
More about : AIFM1 |
| Long gene name: |
apoptosis inducing factor mitochondria associated 1 |
| Synonyms gene: |
PDCD8 NAMSD |
| Synonyms gene name: |
1 apoptosis inducing factor, axonal, mitochondria associated 1 , mitochondrion-associated, motor-sensory with deafness and mental retardation (Cowchock syndrome) apoptosis-inducing factor, programmed cell death 8 (apoptosis-inducing factor) neuropathy |
| Locus: |
Xq26, 1 |
| Discovery year: |
1999-05-28 |
| GenBank acession: |
AF100928 |
| Entrez gene record: |
9131 |
| Pubmed identfication: |
9989411 23217327 |
| Havana BLAST/BLAT: |
OTTHUMG00000022392 |
| Locus Specific Databases: |
Mental Retardation database |