| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Pdx1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the Pdx1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Pdx1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P52946 |
| Purity: |
Antigen affinity |
| Description: |
As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, Binds the DNA sequence 5'-CC[CT]TAATGGG-3', Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element, Activates insulin and somatostatin gene transcription |
| Immunogen: |
This mouse Pdx1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 136-169 amino acids from the Central region of mouse Pdx1 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Pdx1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Pdx1 |
| Short name: |
Pdx1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Pdx1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
43698 |
| Gene: |
PLUT |
More about : PLUT |
| Long gene name: |
PDX1 associated lncRNA, upregulator of transcription |
| Synonyms gene: |
PDX1-AS1 |
| Synonyms gene name: |
PDX1 antisense RNA 1 (non-protein coding) PDX1 antisense RNA 1 |
| Synonyms: |
PLUTO HI-LNC71 |
| Locus: |
13q12, 2 |
| Discovery year: |
2012-01-31 |
| GenBank acession: |
BX383058 CR593175 |
| Pubmed identfication: |
28041957 |
| Havana BLAST/BLAT: |
OTTHUMG00000170578 |