| Long name: |
PDX1 Primary Polyclonal Antibody |
| Also known as: |
PDX1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PDX1 |
| Specificity: |
This is a highly specific antibody against PDX1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
190-222/284 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse PDX1 |
| Gene ID number: |
18609 |
| Swiss Prot: |
P52946 |
| Tested Applications: |
IF(ICC), IHC-P, WB |
| Recommended dilutions: |
IF(ICC)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, Binds the DNA sequence 5'-CC[CT]TAATGGG-3', Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element, Activates insulin and somatostatin gene transcription |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
IDX-1, IPF-1, Insulin promoter factor 1, Islet/duodenum homeobox 1, Mody4, Pancreas/duodenum homeobox protein 1, Pdx1, STF-1, Somatostatin-transactivating factor 1, pdx-1, Ipf1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PDX1 |
| Short name: |
PDX1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PDX1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21350 |
| Gene: |
PDHX |
More about : PDHX |
| Long gene name: |
pyruvate dehydrogenase complex component X |
| Synonyms: |
E3BP proX PDX1 OPDX DLDBP |
| Locus: |
11p13 |
| Discovery year: |
2003-06-24 |
| GenBank acession: |
U82328 |
| Entrez gene record: |
8050 |
| Pubmed identfication: |
9467010 12372595 |
| RefSeq identity: |
NM_003477 |
| Havana BLAST/BLAT: |
OTTHUMG00000166491 |