| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IRAK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the IRAK antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This IRAK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P51617 |
| Purity: |
Purified |
| Description: |
By this basic mechanism, IRAK (interleukin-1 receptor-associated kinase), LISK (LIMK/TESK), RIPK (receptor-interacting protein kinase), Raf, The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains, The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), With more than 500 gene products, and STRK (activin and TGF-beta receptors) families, and differentiation, apoptosis, cell cycle progression, cytoskeletal rearrangement and cell movement, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, the protein kinase family is one of the largest families of proteins in eukaryotes, transcription, Protein kinases are enzymes that transfer a phosphate group from a phosphate donor |
| Immunogen: |
A portion of amino acids 683-712 from the human protein was used as the immunogen for this IRAK antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the IRAK antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IRAK |
| Short name: |
IRAK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IRAK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6112 |
| Gene: |
IRAK1 |
More about : IRAK1 |
| Long gene name: |
interleukin 1 receptor associated kinase 1 |
| Synonyms: |
IRAK pelle |
| Locus: |
Xq28 |
| Discovery year: |
1998-06-22 |
| GenBank acession: |
L76191 |
| Entrez gene record: |
3654 |
| Pubmed identfication: |
9374458 8599092 |
| Havana BLAST/BLAT: |
OTTHUMG00000024228 |
| Locus Specific Databases: |
Mental Retardation database |