| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IRAK-M |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the IRAK-M antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This IRAK-M antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8K4B2 |
| Purity: |
Antigen affinity |
| Description: |
IRAK-M functions as a negative regulator of Toll-like receptor signaling, Members of this family are essential components of the TLR/ILR immune signal transduction pathways, is an enzyme that in humans is encoded by the IRAK3 gene and a member of the interleukin-1 receptor-associated kinase protein family, or Interleukin-1 receptor-associated kinase 3, IL1 receptor associated kinase M (IRAK-M) |
| Immunogen: |
Amino acids KHLWYMPEEYIRQGRL (mouse 349-364) were used as the immunogen for this IRAK-M antibody (100% rat homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IRAK-M antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IRAK-M |
| Short name: |
IRAK-M Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IRAK-M (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17020 |
| Gene: |
IRAK3 |
More about : IRAK3 |
| Long gene name: |
interleukin 1 receptor associated kinase 3 |
| Synonyms gene name: |
interleukin-1 receptor-associated kinase 3 |
| Synonyms: |
IRAK-M |
| Locus: |
12q14, 3 |
| Discovery year: |
2002-07-17 |
| GenBank acession: |
AF113136 |
| Entrez gene record: |
11213 |
| Pubmed identfication: |
10383454 |
| Havana BLAST/BLAT: |
OTTHUMG00000169002 |