| Also known as: |
IRAK1 / IRAK |
| Other names: |
IRAK-1, Interleukin-1 receptor-associated kinase 1, N/A, Pelle homolog, interleukin-1 receptor-associated kinase 1, interleukin-1 receptor-associated kinase 1, interleukin-1 receptor-associated kinase 1 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
IRAK1 |
| Gene name synonims: |
IRAK |
| Other gene names: |
IRAK, IRAK, IRAK-1, IRAK1, pelle, IRAK1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
3A9 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (ELISA), Immunofluorescence (IF), Immunoprecipitation (IP), RNA interference, Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 3A9] (IgG1, k) IRAK1 / IRAK |
| Short name: |
Mouse Monoclonal [clone 3A9] (IgG1, k) IRAK1 / IRAK Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens interleukin-1 receptor-associated kinase 1 / IRAK (Antibody to), Mouse monoclonal [clonality 3A9] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070498 and interleukin-1-mediated signaling pathway and biological process this GO :0070555 and response to interleukin-1 and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071456 and cellular response to hypoxia and biological process, IRAK and pelle, IRAK1 and IDBG-632573 and ENSBTAG00000016085 and 533953, IRAK1 and IDBG-90782 and ENSG00000184216 and 3654, Irak1 and IDBG-154747 and ENSMUSG00000031392 and 16179, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045323 and interleukin-1 receptor complex and cellular component this GO :0045893 and positive regulation of transcription, nuclei, this GO :0000187 and activation of MAPK activity and biological process this GO :0001959 and regulation of cytokine-mediated signaling pathway and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005149 and interleukin-1 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005811 and lipid particle and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007178 and transmembrane receptor protein serine/threonine kinase signaling pathway and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0007254 and JNK cascade and biological process this GO :0007568 and aging and biological process this GO :0008152 and metabolic process and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004704 : NF-kappaB-inducing kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005149 : interleukin-1 receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004704 : NF-kappaB-inducing kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0005149 : interleukin-1 receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0031072 : heat shock protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031072 : heat shock protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032494 and response to peptidoglycan and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0034605 and cellular response to heat and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, interleukin-1 receptor-associated kinase 1 |
| Identity: |
6112 |
| Gene: |
IRAK1 |
More about : IRAK1 |
| Long gene name: |
interleukin 1 receptor associated kinase 1 |
| Synonyms: |
IRAK pelle |
| Locus: |
Xq28 |
| Discovery year: |
1998-06-22 |
| GenBank acession: |
L76191 |
| Entrez gene record: |
3654 |
| Pubmed identfication: |
9374458 8599092 |
| Havana BLAST/BLAT: |
OTTHUMG00000024228 |
| Locus Specific Databases: |
Mental Retardation database |