| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ERBB4 (HER4) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the ERBB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ERBB4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q15303 |
| Purity: |
Purified |
| Description: |
[UniProt], cell proliferation, differentiation, gene transcription, migration and apoptosis, the central nervous system and the mammary gland, ERBB4 is a tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart |
| Immunogen: |
A portion of amino acids 1276-1308 from the human protein was used as the immunogen for this ERBB4 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ERBB4 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ERBB4 (HER4) |
| Short name: |
ERBB4 Antibody (HER4) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (Antibody to) (HER4) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ALS19 and HER4 and p180erbB4, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0007595 and lactation and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, DNA-templated and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0060045 and positive regulation of cardiac muscle cell proliferation and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0061026 and cardiac muscle tissue regeneration and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :2000366 and positive regulation of STAT protein import into nucleus and biological process, ERBB4 and IDBG-643612 and ENSBTAG00000012647 and, ERBB4 and IDBG-79992 and ENSG00000178568 and 2066, Erbb4 and IDBG-164078 and ENSMUSG00000062209 and 13869, nuclei, this GO :0001755 and neural crest cell migration and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005154 and epidermal growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0005154 : epidermal growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0005154 : epidermal growth factor receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0042803 : protein homodimerization activity, this GO :0044212 : transcription regulatory region DNA binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042803 : protein homodimerization activity and also this GO :0044212 : transcription regulatory region DNA binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0021551 and central nervous system morphogenesis and biological process this GO :0021889 and olfactory bulb interneuron differentiation and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042523 and positive regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043235 and receptor complex and cellular component this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0043653 and mitochondrial fragmentation involved in apoptotic process and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045893 and positive regulation of transcription, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) |
| Identity: |
3432 |
| Gene: |
ERBB4 |
More about : ERBB4 |
| Long gene name: |
erb-b2 receptor tyrosine kinase 4 |
| Synonyms gene name: |
v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 |
| Synonyms: |
ALS19 HER4 |
| Synonyms name: |
human epidermal growth factor receptor 4 |
| Locus: |
2q34 |
| Discovery year: |
1995-09-07 |
| GenBank acession: |
L07868 |
| Entrez gene record: |
2066 |
| Pubmed identfication: |
7700649 17018285 |
| RefSeq identity: |
NM_001042599 |
| Classification: |
Erb-b2 receptor tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000133012 |