| Gene info: |
Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, The NMDAR plays an essential role in memory, Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR), epilepsy and ischemic neuronal cell death, memory impaired animals have deficiencies in NR2B expression, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer&rsquo, The ion channels activated by glutamate are typically divided into two classes, s |
| Gene names: |
GluN2B, N-methyl D-aspartate receptor subtype 2B, GluN2B |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Affinity Purified |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Antigen: |
NMDA NR2B polyclonal antibody was made against a C-terminal fusion protein of the NR2B subunit of the NMDAR |
| Immuno application: |
immuno precipitation, immuno-histo-chemistry, Western Blot |
| Antibody advice: |
1:1000-1:2000 for IHC, 3 ug/200 ug lysate will quantitatively precipitate all NMDAR 2B, Applications include Dot Blots (DB), Immunohistochemistry (IHC), Immunolabeling blocked by pre-adsorption of antibody with the C-terminal fusion protein of the NR2B subunit that was used to generate the antibody, Immunolabeling has been demonstrated in human, Immunoprecipitation (IP) and Western Blots (WB), No reactivity towards the NR2A subunit of the NMDAR, When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB, and in IP, mouse and rat tissues, NMDA NR2B Subunit antibody is specific for the 180 kDa NR2B subunit in Western blots of most brain regions |
| Keep at: |
After reconstitution in 50 &, Ambient shipment is suitable for both international and domestic, the antibody should be aliquot and stored at -20 grades C and is stable at -20 grades C for at least 1 year, #956, NMDA NR2B Subunit antibody can be stored at -20 grades C, l PBS |
| Works with: |
Rat, Human |
| Omim nr: |
548372 |
| Ncbi nr: |
Q00960 |
| KDa: |
180 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
24410 |
| GENE symbol: |
Grin2b |
| Antigene name: |
N-methyl D-aspartate 2B, ionotropic, glutamate receptor |
| Source: |
Rattus norvegicus |
| Protein nr: |
Q00960 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
NMDA NR2B |
| Short name: |
anti-NMDA NR2B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-NMDA NR2B (Antibody to) |
| Alternative technique: |
antibodies |