| known also as: |
Anti-RABBIT ANTI RAT NMDA RECEPTOR NR2B (pSer1480) |
| known also as: |
RABBIT ANTI RAT NMDA RECEPTOR NR2B (pSer1480) |
| known also as: |
Lapin ANTI Rattus norvegicus NMDA RECEPTOR NR2B (pSer1480) |
| known also as: |
NMDAR NR2B |
| Other names: |
Glutamate [NMDA] receptor subunit epsilon-2, Glutamate receptor ionotropic, N-methyl D-aspartate 2B, N-methyl D-aspartate receptor subtype 2B, N-methyl D-aspartate receptor subtype 2B, NMDA 2B, NMDA 2B, NMDA 2B, NMDA2B, NMDAR2B, NR2B, glutamate [NMDA] receptor subunit epsilon-2, glutamate receptor, glutamate receptor, glutamate receptor ionotropic, ionotropic, ionotropic, glutamate receptor ionotropic |
| Gene name: |
NMDAR NR2B |
| Other gene names: |
GluN2B, GluN2B, Grin2b, NMDAR2B, NR2B, Grin2b |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Rat |
| Specificity and cross-reactivity: |
E, Properties of NMDAR include modulation by glycine, Receptors for NMDA belong to a group of ionotropic glutamate receptors which play a key role in the mediation of glutamate neurotransmission within the mammalian central nervous system (CNS), Several antagonists and agonists of NMDA receptors (NMDAR) have been identified, Studies have shown that the phosphorylation of the Ser1480 site within the C-terminal PDZ ligand of the NR2B subunit of NMDAR, blockade and high Ca<, by casein kinase II (CK2), including involvement in memory and learning processes, including the glutamate analogue homoquinolinic acid, inhibition by Zn<, results in a decrease in neuron NR2B surface expression The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer's disease (Popke, voltage-dependent Mg<, when phosphorylated at Ser1480, which displays a higher affinity for NR2B-containing NMDAR, ) and also epilepsy and ischemic neuronal cell death, /sup>, /sup>, /sup>, 2+<, 2+<, 2+<, J, NMDAR NR2B This item specifically recognises the 180kDa NR2B subunit of the NMDA (N-methyl-D-aspartate) receptor, permeability, sup>, sup>, sup> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
NMDA RECEPTOR NR2B (pSer1480) |
| Short name: |
Anti-RAT NMDA RECEPTOR NR2B (pSer1480) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-RAT NMDA RECEPTOR NR2B (pSer1480) (Antibody to) |
| Alternative technique: |
antibodies |