| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DR1 protein |
| Specificity: |
This antibody reacts specifically with DR1 protein |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DR1 protein |
| Gene ID: |
10589 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
(DRAP1) to comprise the conserved eukaryotic complex, (negative cofactor 2 subunit â, Both subunits, DR1 forms a heterodimer with NC2&, DR1 localizes to the nucleus and contains an N-terminal histone fold motif, More specifically, NC2 (negative cofactor 2), NC2 activity is regulated by phosphorylation, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription, NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB, NC2&, The NC2 complex can both positively and negatively regulate transcription by RNA Pol II, Via its histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region, also known as NC2â, and DR1, are phosphorylated in vivo, is a TFIID (TATA box-binding protein)-associated protein, &circ, &circ, «, «, ), DR1, aring, aring |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NC2-BETA NC2B |
| Also known as: |
DR1 protein Polyclonal Antibody |
| Other name: |
Anti-DR1 protein Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DR1 protein |
| Short name: |
Anti-DR1 protein (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DR1 protein (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3017 |
| Gene: |
DR1 |
More about : DR1 |
| Long gene name: |
down-regulator of transcription 1 |
| Synonyms gene name: |
TBP-binding (negative cofactor 2) , down-regulator of transcription 1 |
| Synonyms name: |
negative cofactor 2 negative cofactor 2 beta |
| Locus: |
1p22, 1 |
| Discovery year: |
1996-07-11 |
| GenBank acession: |
M97388 |
| Entrez gene record: |
1810 |
| Pubmed identfication: |
1339312 9040789 |
| RefSeq identity: |
NM_001938 |
| Classification: |
ATAC complex |
| Havana BLAST/BLAT: |
OTTHUMG00000010862 |