| Long name: |
Biotin Conjugated, DR1 protein Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DR1 protein |
| Specificity: |
This is a highly specific antibody against DR1 protein |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DR1 protein |
| Gene ID number: |
10589 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
(DRAP1) to comprise the conserved eukaryotic complex, (negative cofactor 2 subunit â, Both subunits, DR1 forms a heterodimer with NC2&, DR1 localizes to the nucleus and contains an N-terminal histone fold motif, More specifically, NC2 (negative cofactor 2), NC2 activity is regulated by phosphorylation, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription, NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB, NC2&, The NC2 complex can both positively and negatively regulate transcription by RNA Pol II, Via its histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region, also known as NC2â, and DR1, are phosphorylated in vivo, is a TFIID (TATA box-binding protein)-associated protein, &circ, &circ, «, «, ), DR1, aring, aring |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
NC2-BETA NC2B |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DR1 protein Conjugated |
| Short name: |
Conjugated, DR1 protein Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, DR1 protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3017 |
| Gene: |
DR1 |
More about : DR1 |
| Long gene name: |
down-regulator of transcription 1 |
| Synonyms gene name: |
TBP-binding (negative cofactor 2) , down-regulator of transcription 1 |
| Synonyms name: |
negative cofactor 2 negative cofactor 2 beta |
| Locus: |
1p22, 1 |
| Discovery year: |
1996-07-11 |
| GenBank acession: |
M97388 |
| Entrez gene record: |
1810 |
| Pubmed identfication: |
1339312 9040789 |
| RefSeq identity: |
NM_001938 |
| Classification: |
ATAC complex |
| Havana BLAST/BLAT: |
OTTHUMG00000010862 |