| Long name: |
ALEXA FLUOR 488 Conjugated, DR1 protein Polyclonal Antibody |
| Also known as: |
Anti-DR1 protein PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DR1 protein |
| Specificity: |
This is a highly specific antibody against DR1 protein |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR1 protein |
| Gene ID Number: |
10589 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
(DRAP1) to comprise the conserved eukaryotic complex, (negative cofactor 2 subunit â, Both subunits, DR1 forms a heterodimer with NC2&, DR1 localizes to the nucleus and contains an N-terminal histone fold motif, More specifically, NC2 (negative cofactor 2), NC2 activity is regulated by phosphorylation, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription, NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB, NC2&, The NC2 complex can both positively and negatively regulate transcription by RNA Pol II, Via its histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region, also known as NC2â, and DR1, are phosphorylated in vivo, is a TFIID (TATA box-binding protein)-associated protein, &circ, &circ, «, «, ), DR1, aring, aring |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
NC2-BETA NC2B |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DR1 protein Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
DR1 protein |
| Short name: |
DR1 protein Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, DR1 protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3017 |
| Gene: |
DR1 |
More about : DR1 |
| Long gene name: |
down-regulator of transcription 1 |
| Synonyms gene name: |
TBP-binding (negative cofactor 2) , down-regulator of transcription 1 |
| Synonyms name: |
negative cofactor 2 negative cofactor 2 beta |
| Locus: |
1p22, 1 |
| Discovery year: |
1996-07-11 |
| GenBank acession: |
M97388 |
| Entrez gene record: |
1810 |
| Pubmed identfication: |
1339312 9040789 |
| RefSeq identity: |
NM_001938 |
| Classification: |
ATAC complex |
| Havana BLAST/BLAT: |
OTTHUMG00000010862 |