| Long name: |
DR1 protein Primary Polyclonal Antibody |
| Also known as: |
DR1 protein PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DR1 protein |
| Specificity: |
This is a highly specific antibody against DR1 protein |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR1 protein |
| Gene ID number: |
10589 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
(DRAP1) to comprise the conserved eukaryotic complex, (negative cofactor 2 subunit â, Both subunits, DR1 forms a heterodimer with NC2&, DR1 localizes to the nucleus and contains an N-terminal histone fold motif, More specifically, NC2 (negative cofactor 2), NC2 activity is regulated by phosphorylation, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription, NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB, NC2&, The NC2 complex can both positively and negatively regulate transcription by RNA Pol II, Via its histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region, also known as NC2â, and DR1, are phosphorylated in vivo, is a TFIID (TATA box-binding protein)-associated protein, &circ, &circ, «, «, ), DR1, aring, aring |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DR 1, Down regulator of transcription 1, Down regulator of transcription 1 TBP binding, Down-regulator of transcription 1, Dr1, NC 2, NC2, NC2 beta, NC2-beta, NC2B_HUMAN, Negative co factor 2, Negative cofactor 2, Negative cofactor 2 beta, Negative cofactor 2-beta, Protein Dr1, TATA binding protein associated phosphoprotein, TATA-binding protein-associated phosphoprotein, Dr1 protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DR1 protein |
| Short name: |
DR1 protein Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DR1 protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3017 |
| Gene: |
DR1 |
More about : DR1 |
| Long gene name: |
down-regulator of transcription 1 |
| Synonyms gene name: |
TBP-binding (negative cofactor 2) , down-regulator of transcription 1 |
| Synonyms: |
NC2-BETA NC2B |
| Synonyms name: |
negative cofactor 2 negative cofactor 2 beta |
| Locus: |
1p22, 1 |
| Discovery year: |
1996-07-11 |
| GenBank acession: |
M97388 |
| Entrez gene record: |
1810 |
| Pubmed identfication: |
1339312 9040789 |
| RefSeq identity: |
NM_001938 |
| Classification: |
ATAC complex |
| Havana BLAST/BLAT: |
OTTHUMG00000010862 |