Anti-CRMP2 (Thr514+Ser518), ALEXA Fluor 594

Catalog number:	GENTAUR-58be6639b3e17 Buy Now
Price:	516 €
Supplier:	Bioss Polyclonal Antibodies
Product name:	Anti-CRMP2 (Thr514+Ser518), ALEXA Fluor 594
Quantity:	100 microliters
Related search:	crmp thrser antibody gene alexa crmps fluor identity

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	CRMP2 Thr514+Ser518
Specificity:	This antibody reacts specifically with CRMP2 (Thr514+Ser518)
Modification:	Phosphorylation
Modification site:	Thr514+Ser518
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Antigen Source:	KLH conjugated synthetic phosphopeptide derived from human CRMP2 around the phosphorylation site of Thr514+Ser518
Gene ID:	1808
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly, CRMP2 is upregulated after axotomy, CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification, CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome, CRMPs localize to the lamellipodia and filopodia of axonal growth cones, Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease, Interaction studies have implicated phospholipase D2 (PLD2), Moreover, The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction, and appears to increase the formation of axon-type processes from hippocampal neurons, and intersectin in CRMP function, suggesting a role in axon guidance, the cytosolic tyrosine kinase Fes, Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Synonyms:	DRP-2 DHPRP2 CRMP2 DRP2
Also known as:	CRMP2 (Thr514+Ser518) Antibody
Other name:	Anti-CRMP2 (Thr514+Ser518)
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	CRMP2 (Thr514+Ser518)
Short name:	Anti-CRMP2 (Thr514+Ser518) Fluor 594
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-CRMP2 (Thr514+Ser518)
Identity:	3014
Gene:	DPYSL2 | More about : DPYSL2
Long gene name:	dihydropyrimidinase like 2
Synonyms gene name:	dihydropyrimidinase-like 2
Locus:	8p21, 2
Discovery year:	1997-02-27
GenBank acession:	D78013
Entrez gene record:	1808
Pubmed identfication:	8973361
RefSeq identity:	NM_001386
Havana BLAST/BLAT:	OTTHUMG00000099439

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