CRMP2 (Thr514+Ser518) Antibody

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Catalog number: bs-8284R
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Supplier: genways bulk
Product name: CRMP2 (Thr514+Ser518) Antibody
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Long name: CRMP2 (Thr514+Ser518) Antibody
Also known as: CRMP2 (Thr514+Ser518) Antibody
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: CRMP2 Thr514+Ser518
Specificity: This is a highly specific antibody against CRMP2 Thr514+Ser518
Modification(s): Phosphorylation
Modification site(s): Thr514+Ser518
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human CRMP2 around the phosphorylation site of Thr514+Ser518
Gene ID number: 1808
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly, CRMP2 is upregulated after axotomy, CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification, CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome, CRMPs localize to the lamellipodia and filopodia of axonal growth cones, Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease, Interaction studies have implicated phospholipase D2 (PLD2), Moreover, The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction, and appears to increase the formation of axon-type processes from hippocampal neurons, and intersectin in CRMP function, suggesting a role in axon guidance, the cytosolic tyrosine kinase Fes, Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: CRAM, CRMP 2, CRMP-2phospho Thr514+S518, CRMP2 phospho T514+S518, CRMP2/Dpysl2DRP 2, Collapsin response mediator protein 2, Collapsin response mediator protein hCRMP 2, DHPRP 2, DHPRP2, DPYL 2, DPYL2, DPYSL 2, DPYSL2, DRP 2, DRP2, Dihydr pyrimidinase 2, Dihydropyrimidinase 2, Dihydropyrimidinase like 2, Dihydropyrimidinase like 2 long form, Musunc 33, Musunc33, N2A3, TOAD 64, TOAD64, ULIP 2 protein, Ulip2, p-CRMP2Thr514+S518, CRMP2 phospho T514 + S518, Dihydropyrimidinase related protein 2
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: CRMP2 (Thr514+Ser518)
Short name: CRMP2 (Thr514+Ser518) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: CRMP2 (Thr514+Ser518) (Antibody to)
Alternative technique: antibodies
Identity: 3014
Gene: DPYSL2 | More about : DPYSL2
Long gene name: dihydropyrimidinase like 2
Synonyms gene name: dihydropyrimidinase-like 2
Synonyms: DRP-2 DHPRP2 CRMP2 DRP2
Locus: 8p21, 2
Discovery year: 1997-02-27
GenBank acession: D78013
Entrez gene record: 1808
Pubmed identfication: 8973361
RefSeq identity: NM_001386
Havana BLAST/BLAT: OTTHUMG00000099439

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