| Catalog number: | bs-8284R-A350 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | CRMP2 (Thr514+Ser518) Antibody, ALEXA FLUOR 350 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, CRMP2 (Thr514+Ser518) Antibody |
|---|---|
| Also known as: | Anti-CRMP2 Thr514+Ser518 PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | CRMP2 Thr514+Ser518 |
| Specificity: | This is a highly specific antibody against CRMP2 Thr514+Ser518 |
| Modification: | Phosphorylation |
| Modification Site: | Thr514+Ser518 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human CRMP2 around the phosphorylation site of Thr514+Ser518 |
| Gene ID Number: | 1808 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly, CRMP2 is upregulated after axotomy, CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification, CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome, CRMPs localize to the lamellipodia and filopodia of axonal growth cones, Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease, Interaction studies have implicated phospholipase D2 (PLD2), Moreover, The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction, and appears to increase the formation of axon-type processes from hippocampal neurons, and intersectin in CRMP function, suggesting a role in axon guidance, the cytosolic tyrosine kinase Fes, Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | DRP-2 DHPRP2 CRMP2 DRP2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | CRMP2 (Thr514+Ser518) |
| Short name: | CRMP2 (Thr514+Ser518) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, CRMP2 (Thr514+Ser518) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 3014 |
| Gene: | DPYSL2 | More about : DPYSL2 |
| Long gene name: | dihydropyrimidinase like 2 |
| Synonyms gene name: | dihydropyrimidinase-like 2 |
| Locus: | 8p21, 2 |
| Discovery year: | 1997-02-27 |
| GenBank acession: | D78013 |
| Entrez gene record: | 1808 |
| Pubmed identfication: | 8973361 |
| RefSeq identity: | NM_001386 |
| Havana BLAST/BLAT: | OTTHUMG00000099439 |
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| bs-3068R-FITC | CRMP2 (Thr514) Antibody, FITC Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
| bs-3068R-HRP | CRMP2 (Thr514) Antibody, HRP Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
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