| Long name: |
FITC Conjugated, CRMP2 (Thr514+Ser518) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CRMP2 Thr514+Ser518 |
| Specificity: |
This is a highly specific antibody against CRMP2 Thr514+Ser518 |
| Modification: |
Phosphorylation |
| Modification site: |
Thr514+Ser518 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CRMP2 around the phosphorylation site of Thr514+Ser518 |
| Gene ID number: |
1808 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly, CRMP2 is upregulated after axotomy, CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification, CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome, CRMPs localize to the lamellipodia and filopodia of axonal growth cones, Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease, Interaction studies have implicated phospholipase D2 (PLD2), Moreover, The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction, and appears to increase the formation of axon-type processes from hippocampal neurons, and intersectin in CRMP function, suggesting a role in axon guidance, the cytosolic tyrosine kinase Fes, Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
DRP-2 DHPRP2 CRMP2 DRP2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CRMP2 (Thr514+Ser518) Conjugated |
| Short name: |
FITC Conjugated, CRMP2 (Thr514+Ser518) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CRMP2 (Thr514+Ser518) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3014 |
| Gene: |
DPYSL2 |
More about : DPYSL2 |
| Long gene name: |
dihydropyrimidinase like 2 |
| Synonyms gene name: |
dihydropyrimidinase-like 2 |
| Locus: |
8p21, 2 |
| Discovery year: |
1997-02-27 |
| GenBank acession: |
D78013 |
| Entrez gene record: |
1808 |
| Pubmed identfication: |
8973361 |
| RefSeq identity: |
NM_001386 |
| Havana BLAST/BLAT: |
OTTHUMG00000099439 |