| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PP1A/PP2CA/PPP1CA |
| Specificity: |
This antibody reacts specifically with PP1A/PP2CA/PPP1CA |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PP1A/PP2CA |
| Gene ID: |
5499 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It binds to magnesium or manganese ions and exists as a monomer, It is essential for cell division, PPP1A is involved in the regulation long term synaptic plasticity and may play an important role in dephosphorylating substrates such as Ca2+/calmodulin dependent protein kinase II, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis, PPP1A is a serine/threonine protein phosphatase catalytic subunit that is essential for regulating cellular stress responses in eukaryotes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PP1A PP-1A PP1alpha |
| Also known as: |
PP1A/PP2CA/PPP1CA Polyclonal Antibody |
| Other name: |
Anti-PP1A/PP2CA/PPP1CA Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PP1A/PP2CA/PPP1CA |
| Short name: |
Anti-PP1A/PP2CA/PPP1CA (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PP1A/PP2CA/PPP1CA (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9281 |
| Gene: |
PPP1CA |
More about : PPP1CA |
| Long gene name: |
protein phosphatase 1 catalytic subunit alpha |
| Synonyms gene: |
PPP1A |
| Synonyms gene name: |
alpha isoform protein phosphatase 1, alpha isozyme , catalytic subunit, catalytic subunit, protein phosphatase 1 |
| Locus: |
11q13 |
| Discovery year: |
1989-10-11 |
| Entrez gene record: |
5499 |
| RefSeq identity: |
NM_002708 |
| Classification: |
Protein phosphatase catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000167671 |