| Long name: |
Biotin Conjugated, PP2CA Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PP2CA |
| Specificity: |
This is a highly specific antibody against PP2CA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PP2CA |
| Gene ID number: |
5494 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses, Jul 2008], MAP kinases and MAP kinase kinases, Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, PP2C family members are known to be negative regulators of cell stress response pathways, This phosphatase can also dephosphorylate cyclin-dependent kinases, This phosphatase dephosphorylates, Three alternatively spliced transcript variants encoding distinct isoforms have been described, [provided by RefSeq, and negatively regulates the activities of, and thus may be involved in cell cycle control, which leads to G2/M cell cycle arrest and apoptosis, The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
MGC9201 PP2Calpha PP2CA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PP2CA Conjugated |
| Short name: |
Conjugated, PP2CA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PP2CA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9275 |
| Gene: |
PPM1A |
More about : PPM1A |
| Long gene name: |
Mg2+/Mn2+ dependent 1A , protein phosphatase |
| Synonyms gene name: |
1A , Mg2+/Mn2+ dependent, alpha isoform protein phosphatase, magnesium-dependent, protein phosphatase 1A (formerly 2C) |
| Synonyms name: |
alpha isoform , phosphatase 2C alpha protein phosphatase 2C |
| Locus: |
14q23, 1 |
| Discovery year: |
1993-02-05 |
| GenBank acession: |
S87759 |
| Entrez gene record: |
5494 |
| Pubmed identfication: |
1311954 |
| RefSeq identity: |
NM_021003 |
| Classification: |
Mg2+/Mn2+ dependent , Protein phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000140333 |