| Long name: |
ALEXA FLUOR 350 Conjugated, PP2CA Polyclonal Antibody |
| Also known as: |
Anti-PP2CA PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PP2CA |
| Specificity: |
This is a highly specific antibody against PP2CA |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PP2CA |
| Gene ID Number: |
5494 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses, Jul 2008], MAP kinases and MAP kinase kinases, Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, PP2C family members are known to be negative regulators of cell stress response pathways, This phosphatase can also dephosphorylate cyclin-dependent kinases, This phosphatase dephosphorylates, Three alternatively spliced transcript variants encoding distinct isoforms have been described, [provided by RefSeq, and negatively regulates the activities of, and thus may be involved in cell cycle control, which leads to G2/M cell cycle arrest and apoptosis, The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
MGC9201 PP2Calpha PP2CA |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
PP2CA |
| Short name: |
PP2CA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, PP2CA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9275 |
| Gene: |
PPM1A |
More about : PPM1A |
| Long gene name: |
Mg2+/Mn2+ dependent 1A , protein phosphatase |
| Synonyms gene name: |
1A , Mg2+/Mn2+ dependent, alpha isoform protein phosphatase, magnesium-dependent, protein phosphatase 1A (formerly 2C) |
| Synonyms name: |
alpha isoform , phosphatase 2C alpha protein phosphatase 2C |
| Locus: |
14q23, 1 |
| Discovery year: |
1993-02-05 |
| GenBank acession: |
S87759 |
| Entrez gene record: |
5494 |
| Pubmed identfication: |
1311954 |
| RefSeq identity: |
NM_021003 |
| Classification: |
Mg2+/Mn2+ dependent , Protein phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000140333 |