| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Estrogen Receptor alpha + beta |
| Specificity: |
This antibody reacts specifically with Estrogen Receptor alpha + beta |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Estradiol Receptor alpha + beta |
| Gene ID: |
2099, 2100 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A second form of the estrogen receptor, ER beta has recently been described, It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors, Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e, The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons, The ER is an important regulator of growth and differentiation in the mammary gland, These translate into a protein with six functionally discrete domains, labeled A through F, tamoxifen) therapy, The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues, g |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Atherosclerosis, DKFZp686N23123, ER, ER Alpha, ER Beta, ER-alpha, ER-beta, ER[a], ER[b], ERalpha, ERbeta, ESR, ESR BETA, ESR1, ESR1_HUMAN, ESR2, ESRA, ESRB, ESTRB, Era, Erb, Erb2, Estr, Estra, Estradiol Receptor alpha, Estradiol Receptor beta, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor 2, Estrogen receptor, Estrogen receptor 1 alpha, Estrogen receptor 2 ER beta, Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor beta 4, Estrogen resistance, HDL cholesterol, Myocardial infarction, NR3A1, NR3A2, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR, augmented response of, included, included, included, included, susceptibility to, susceptibility to, to hormone replacement, Estrogen Receptor alpha/beta |
| Also known as: |
Estrogen Receptor alpha + beta Antibody |
| Other name: |
Anti-Estrogen Receptor alpha + beta |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Estrogen Receptor alpha + beta |
| Short name: |
Fluor 594, Anti-Estrogen Receptor alpha + beta |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Estrogen Receptor a and b |