| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Estrogen Receptor beta Ser87 |
| Specificity: |
This antibody reacts specifically with Estrogen Receptor beta (Ser87) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser87 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Estrogen Receptor beta around the phosphorylation site of Ser87 [HL(p-S)PL] |
| Gene ID: |
2100 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ER alpha and ER beta A have been shown to be differentially activated by various ligands, Estrogen receptors, Evidence suggests that ER alpha and ER beta may be regulated by distinct mechanisms even though they share many functional characteristics, Receptor-ligand interactions trigger a cascade of events, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues, including ER alpha and ER beta, including dissociation from heat shock proteins, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes, receptor dimerization, Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ER BETA, ER-BETA, ER-beta, ER-betaS87, ER-betaSer87, ESR 2, ESR 2, ESR B, ESR BETA, ESR-B, ESR-BETA, ESR2, ESR2, ESR2_HUMAN, ESRB, ESTRB, Erb, Estrogen Receptor 2, Estrogen Receptor beta phospho Ser87, Estrogen Receptor-2, Estrogen receptor beta, Estrogen receptor-beta, NR3A2, Nuclear receptor subfamily 3 group A member 2, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 ER beta, estrogen receptor beta 4, p-ER betaS87, p-ER betaSer87, Estrogen Receptor beta phospho S87 |
| Also known as: |
Estrogen Receptor beta (Ser87) Antibody |
| Other name: |
Anti-Estrogen Receptor beta (Ser87) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Estrogen Receptor beta (Ser87) |
| Short name: |
Anti-Estrogen Receptor beta (Ser87) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Estrogen Receptor b (Ser87) |