| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
GLUR3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the GLUR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This GLUR3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P42263 |
| Purity: |
Antigen affinity |
| Description: |
GLUR3 has been shown to interact with GRIP1 and PICK1, Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes, In addition, It is mapped to Xq25, The classification of glutamate receptors is based on their activation by different pharmacologic agonists, These receptors are heteromeric protein complexes with multiple subunits, This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors, and all arranged to form a ligand-gated ion channel, each possessing transmembrane regions, Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene |
| Immunogen: |
mouse and rat), An amino acid sequence from the middle region of human Glutamate receptor 3 (RKAGYWNEYERFVPFSDQQ) was used as the immunogen for this GLUR3 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the GLUR3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
GLUR3 |
| Short name: |
GLUR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GLUR3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4573 |
| Gene: |
GRIA3 |
More about : GRIA3 |
| Long gene name: |
glutamate ionotropic receptor AMPA type subunit 3 |
| Synonyms gene: |
GLUR3 |
| Synonyms gene name: |
AMPA 3 , glutamate receptor, ionotrophic |
| Synonyms: |
GluA3 GLURC MRX94 |
| Locus: |
Xq25 |
| Discovery year: |
1992-02-26 |
| GenBank acession: |
U10301 |
| Entrez gene record: |
2892 |
| Pubmed identfication: |
1319477 10644433 |
| RefSeq identity: |
NM_000828 |
| Classification: |
Glutamate ionotropic receptor AMPA type subunits X-linked mental retardation |
| Havana BLAST/BLAT: |
OTTHUMG00000022685 |
| Locus Specific Databases: |
Mental Retardation database |