| Long name: |
GLUR3 Primary Polyclonal Antibody |
| Also known as: |
GLUR3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GLUR3/GRIA 3 |
| Specificity: |
This is a highly specific antibody against GLUR3/GRIA 3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
440-490/894 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GLUR3 |
| Gene ID number: |
2892 |
| Swiss Prot: |
P42263 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, In the presence of CACNG4 or CACNG7 or CACNG8, L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system, The receptor then desensitizes rapidly and enters a transient inactive state, and thereby converts the chemical signal to an electrical impulse, characterized by the presence of bound agonist, leading to the opening of the cation channel, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate, Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AMPA 3, AMPA-selective glutamate receptor 3, GLUR-C, GLUR-K3, GLURC, GRIA3, GluA3, GluR-3, Glutamate receptor 3, Glutamate receptor ionotropic, MRX94, GLUR3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GLUR3 |
| Short name: |
GLUR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GLUR3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4573 |
| Gene: |
GRIA3 |
More about : GRIA3 |
| Long gene name: |
glutamate ionotropic receptor AMPA type subunit 3 |
| Synonyms gene: |
GLUR3 |
| Synonyms gene name: |
AMPA 3 , glutamate receptor, ionotrophic |
| Synonyms: |
GluA3 GLURC MRX94 |
| Locus: |
Xq25 |
| Discovery year: |
1992-02-26 |
| GenBank acession: |
U10301 |
| Entrez gene record: |
2892 |
| Pubmed identfication: |
1319477 10644433 |
| RefSeq identity: |
NM_000828 |
| Classification: |
Glutamate ionotropic receptor AMPA type subunits X-linked mental retardation |
| Havana BLAST/BLAT: |
OTTHUMG00000022685 |
| Locus Specific Databases: |
Mental Retardation database |