| Long name: |
Biotin Conjugated, GLUR3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GLUR3/GRIA 3 |
| Specificity: |
This is a highly specific antibody against GLUR3/GRIA 3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
440-490/894 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GLUR3 |
| Gene ID number: |
2892 |
| Swiss Prot: |
P42263 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, In the presence of CACNG4 or CACNG7 or CACNG8, L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system, The receptor then desensitizes rapidly and enters a transient inactive state, and thereby converts the chemical signal to an electrical impulse, characterized by the presence of bound agonist, leading to the opening of the cation channel, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate, Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
GluA3 GLURC MRX94 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GLUR3 Conjugated |
| Short name: |
Conjugated, GLUR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GLUR3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4573 |
| Gene: |
GRIA3 |
More about : GRIA3 |
| Long gene name: |
glutamate ionotropic receptor AMPA type subunit 3 |
| Synonyms gene: |
GLUR3 |
| Synonyms gene name: |
AMPA 3 , glutamate receptor, ionotrophic |
| Locus: |
Xq25 |
| Discovery year: |
1992-02-26 |
| GenBank acession: |
U10301 |
| Entrez gene record: |
2892 |
| Pubmed identfication: |
1319477 10644433 |
| RefSeq identity: |
NM_000828 |
| Classification: |
Glutamate ionotropic receptor AMPA type subunits X-linked mental retardation |
| Havana BLAST/BLAT: |
OTTHUMG00000022685 |
| Locus Specific Databases: |
Mental Retardation database |