| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Proprotein Convertase 2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Proprotein Convertase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Proprotein Convertase 2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P16519 |
| Purity: |
Antigen affinity |
| Description: |
2, Analysis of the level of CAT activity with several deletion mutants identified the region from -1100 to -539 from the translation start site as essential for PC2 promoter activity, Ohagi et al, Seidah et al, Subtilisin/Kexin-Type, also known as PC2 or NEC2, consistent with the known tissue-specific pattern of expression of the gene, is an enzyme responsible for the first step in the maturation of many neuroendocrine peptides from their precursors, such as the conversion of proinsulin to insulin intermediates, (1991) mapped the gene to human chromosome 20p11, (1992) observed expression of the chloramphenicol acetyltransferase reporter fusions containing the putative promoter region in insulinoma cells but not in hepatoma cells, 1, 2-p11, Proprotein Convertase |
| Immunogen: |
mouse and rat), An amino acid sequence from the N-terminus of human Proprotein Convertase 2 (GYRDINEIDINMNDPL) was used as the immunogen for this Proprotein Convertase 2 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Proprotein Convertase 2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Proprotein Convertase 2 |
| Short name: |
Proprotein Convertase 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Proprotein Convertase 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8744 |
| Gene: |
PCSK2 |
More about : PCSK2 |
| Long gene name: |
proprotein convertase subtilisin/kexin type 2 |
| Synonyms gene: |
NEC2 |
| Synonyms: |
PC2 SPC2 |
| Synonyms name: |
neuroendocrine convertase 2 KEX2-like endoprotease 2 |
| Locus: |
20p12, 1 |
| Discovery year: |
1991-06-07 |
| GenBank acession: |
AK312341 |
| Entrez gene record: |
5126 |
| Pubmed identfication: |
1765368 |
| RefSeq identity: |
NM_002594 |
| Classification: |
Proprotein convertase subtilisin/kexin family |
| Havana BLAST/BLAT: |
OTTHUMG00000031941 |