| Long name: |
Polyclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) |
| Antigen: |
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) |
| Other names: |
NARC-1, Neural apoptosis-regulated convertase 1, PC9, Proprotein convertase 9, Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9, convertase subtilisin/kexin type 9 preproprotein, neural apoptosis regulated convertase 1, proprotein convertase subtilisin/kexin type 9, proprotein convertase subtilisin/kexin type 9, subtilisin/kexin-like protease PC9, proprotein convertase subtilisin/kexin type 9 preproprotein |
| Gene name: |
PCSK9, Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) |
| Gene synonims: |
FH3, HCHOLA3, LDLCQ1, NARC-1, NARC-1, NARC1, NARC1, PC9, PC9, PCSK9, PCSK9 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
, It has been selected for its ability to recognize PCSK9 in immunohistochemical staining andwestern blotting, PCSK9, The antibody is a rabbit polyclonal antibody raised against PCSK9, This is an antibody designed to detect Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) |
| Purification method: |
This antibody was purified via Affinity Chromatography |
| Form/Appearance: |
containing 0, pH7, 02% NaN3, 4, 50% glycerol, Supplied as solution form in PBS |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Immunohistochemistry (IHC) - Formalin/Paraffin, Western Blot (WB), Immunocytochemistry (ICC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Gene target: |
Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) |
| Short name: |
Anti- Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Antibody to Proprotein Convertase Subtilisin/Kexin classification 9 (proprotein convertase subtilisin/kexin classification 9) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, PCSK9 and IDBG-99082 and ENSG00000169174 and 255738, Pcsk9 and IDBG-170186 and ENSMUSG00000044254 and 100102, this GO :0001822 and kidney development and biological process this GO :0001889 and liver development and biological process this GO :0001920 and negative regulation of receptor recycling and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005791 and rough endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007041 and lysosomal transport and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0009986 and cell surface and cellular component this GO :0010469 and regulation of receptor activity and biological process this GO :0010989 and negative regulation of low-density lipoprotein particle clearance and biological process this GO :0016485 and protein processing and biological process this GO :0016540 and protein autoprocessing and biological process this GO :0019871 and sodium channel inhibitor activity and molecular function this GO :0022008 and neurogenesis and biological process this GO :0030134 and ER to this GO lgi transport vesicle and cellular component this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030182 and neuron differentiation and biological process this GO :0031232 and extrinsic component of external side of plasma membrane and cellular component this GO :0032799 and low-density lipoprotein receptor particle metabolic process and biological process this GO :0032802 and low-density lipoprotein particle receptor catabolic process and biological process this GO :0032803 and regulation of low-density lipoprotein particle receptor catabolic process and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0034189 and very-low-density lipoprotein particle binding and molecular function this GO :0034190 and apolipoprotein receptor binding and molecular function this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0043621 and protein self-association and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050750 and low-density lipoprotein particle receptor binding and molecular function this GO :0070326 and very-low-density lipoprotein particle receptor binding and molecular function, this GO :0004252 : serine-type endopeptidase activity, this GO :0004252 : serine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0019871 : sodium channel inhibitor activity and also this GO :0030169 : low-density lipoprotein particle binding and also this GO :0034185 : apolipoprotein binding and also this GO :0034189 : very-low-density lipoprotein particle binding and also this GO :0034190 : apolipoprotein receptor binding and also this GO :0043621 : protein self-association and also this GO :0044822 : poly(A) RNA binding and also this GO :0050750 : low-density lipoprotein particle receptor binding and also this GO :0070326 : very-low-density lipoprotein particle receptor binding, this GO :0005515 : protein binding, this GO :0019871 : sodium channel inhibitor activity, this GO :0030169 : low-density lipoprotein particle binding, this GO :0034185 : apolipoprotein binding, this GO :0034189 : very-low-density lipoprotein particle binding, this GO :0034190 : apolipoprotein receptor binding, this GO :0043621 : protein self-association, this GO :0044822 : poly(A) RNA binding, this GO :0050750 : low-density lipoprotein particle receptor binding, this GO :0070326 : very-low-density lipoprotein particle receptor binding, very-low-density lipoprotein particle receptor binding, proprotein convertase subtilisin/kexin type 9 |
| Identity: |
20001 |
| Gene: |
PCSK9 |
More about : PCSK9 |
| Long gene name: |
proprotein convertase subtilisin/kexin type 9 |
| Synonyms gene: |
HCHOLA3 |
| Synonyms gene name: |
autosomal dominant 3 , hypercholesterolemia |
| Synonyms: |
NARC-1 FH3 |
| Locus: |
1p32, 3 |
| Discovery year: |
2003-05-13 |
| GenBank acession: |
AX207686 |
| Entrez gene record: |
255738 |
| Pubmed identfication: |
12552133 12730697 |
| RefSeq identity: |
NM_174936 |
| Classification: |
Proprotein convertase subtilisin/kexin family |
| Havana BLAST/BLAT: |
OTTHUMG00000008136 |
| Locus Specific Databases: |
British Heart Foundation LRG_275 |