| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Proprotein Convertase 1/3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Proprotein Convertase 1/3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Proprotein Convertase 1/3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P29120 |
| Purity: |
Antigen affinity |
| Description: |
1, By in situ hybridization, By observing the phenotypic features in patients with PCSK1 mutations, It is a neuroendocrine convertase that belongs to a family of subtilisin-like serine endoproteases that process large precursor proteins into mature bioactive products, Jackson et al, Ohagi et al, Seidah et al, Subtilisin/Kexin-Type, also known as PC1 or NEC1, arg31-arg32, is an enzyme that in humans is encoded by the PCSK1 gene, joining the B-chain and C-peptide, (1991) mapped the gene to human chromosome 5q15-q21 and mouse chromosome 13, (1996) noted that PCSK1 initiates the sequential processing of proinsulin to insulin by cleaving the proinsulin molecule on the C-terminal side of the dibasic peptide, (2003) concluded that human intestinal absorptive function is dependent on the enzymes activity, Proprotein Convertase |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human Proprotein Convertase 1/3 (DVFYNTKPYKHRDDR) was used as the immunogen for this Proprotein Convertase 1/3 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Proprotein Convertase 1/3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Proprotein Convertase 1/3 |
| Short name: |
Proprotein Convertase 1/3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Proprotein Convertase 1/3 (Antibody to) |
| Alternative technique: |
antibodies |