| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Proprotein Convertase 4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Proprotein Convertase 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Proprotein Convertase 4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P29121 |
| Purity: |
Antigen affinity |
| Description: |
4, IGF2(1-102), Inhibition of the protein by a PCSK4-specific inhibitor blocked pro-IGF2 processing and reduced trophoblast cell migration, Mature IGF2(1-67), PCSK4 cleaved pro-IGF2 to generate the intermediate processed form, Qiu et al, Subtilisin/Kexin-Type, The gene was mapped to mouse chromosome 10, close to the adipsin locus and near the gene encoding anti-mullerian hormone, is an enzyme that in humans is encoded by the PCSK4 gene, is capable of activating invasive trophoblast cells through AKT phosphorylation, likely resulting from further processing by carboxypeptidases, (2005) found that aberrant processing of pro-IGF2 may be a cause of IUGR, Proprotein Convertase |
| Immunogen: |
An amino acid sequence from the N-terminus of mouse Proprotein convertase 4 (DPWFSKQWYMNKEIQQD) was used as the immunogen for this Proprotein Convertase 4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Proprotein Convertase 4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Proprotein Convertase 4 |
| Short name: |
Proprotein Convertase 4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Proprotein Convertase 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8569 |
| Gene: |
PCSK6 |
More about : PCSK6 |
| Long gene name: |
proprotein convertase subtilisin/kexin type 6 |
| Synonyms gene: |
PACE4 |
| Synonyms gene name: |
paired basic amino acid cleaving system 4 |
| Synonyms: |
SPC4 |
| Synonyms name: |
subtilisin-like protease subtilisin-like proprotein convertase 4 subtilisin/kexin-like protease PACE4 |
| Locus: |
15q26 |
| Discovery year: |
1992-06-05 |
| Entrez gene record: |
5046 |
| Pubmed identfication: |
1741956 |
| RefSeq identity: |
NM_002570 |
| Classification: |
Proprotein convertase subtilisin/kexin family |
| Havana BLAST/BLAT: |
OTTHUMG00000172097 |
| Locus Specific Databases: |
LRG_888 |