| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RANK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the RANK antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This RANK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y6Q6 |
| Purity: |
Antigen affinity |
| Description: |
Anderson et al, By analysis of somatic cell and radiation hybrid panels, RANK is also expressed on dendritic cells and facilitates immune signaling, RANKL (Receptor Activator for Nuclear Factor K B Ligand) is found on the surface of stromal cells, also known as TRANCE Receptor, and T cells, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding, osteoblasts, (1997) mapped the RANK gene to 18q22, 1, Receptor Activator of Nuclear Factor K B |
| Immunogen: |
An amino acid sequence from the N-terminus of human RANK (QIAPPCTSEKHYEHLG) was used as the immunogen for this RANK antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RANK antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RANK |
| Short name: |
RANK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RANK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11908 |
| Gene: |
TNFRSF11A |
More about : TNFRSF11A |
| Long gene name: |
TNF receptor superfamily member 11a |
| Synonyms gene: |
PDB2 LOH18CR1 |
| Synonyms gene name: |
18, NFKB activator , activator of NFKB Paget disease of bone 2 loss of heterozygosity, chromosomal region 1 tumor necrosis factor receptor superfamily, member 11a, member 11a, tumor necrosis factor receptor superfamily |
| Synonyms: |
RANK CD265 FEO |
| Locus: |
18q21, 33 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF018253 |
| Entrez gene record: |
8792 |
| Pubmed identfication: |
9367155 10615125 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000132779 |
| Locus Specific Databases: |
LRG_194 |