RANK Antibody, ALEXA FLUOR 555

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Catalog number: bs-7343R-A555
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: RANK Antibody, ALEXA FLUOR 555
Quantity: 100ul
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Long name: ALEXA FLUOR 555 Conjugated, RANK Polyclonal Antibody
Also known as: Anti-RANK PAb ALEXA FLUOR 555
Category: Conjugated Primary Antibodies
Conjugated with: 555, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: RANK
Specificity: This is a highly specific antibody against RANK
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Subcellular location: Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RANK
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: CD265 is also expressed in dendritic cells, CD265 is widely expressed, Human and murine CD265 share 81% amino acid identity in their extracellular domains, Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of CD265, RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells, RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis, TRANCE (TNF-related activation-induced cytokines, The binding of anti-CD265 to cell surface CD265 triggers signal transduction and induces CD265 mediated bioactivity, The biological functions mediated by RANK include activation of NFkappaB and cjun N-terminal kinase, The soluble form of CD265 is able to block TRANCE induced biological activity, also known as RANK ligand, colon, enhancement of T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis, liver, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for CD265, small intestine and adrenal gland, thymus, with highest levels in skeletal muscle, CD265 is a member of the tumor necrosis factor receptor (TNFR) family
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 553nm/568nm
Synonyms: RANK CD265 FEO
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 555, Alexa Fluor
Gene target: RANK
Short name: RANK Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 555
Alternative name: ALEXA FLUOR 555, RANK (Antibody to)
Alternative technique: antibodies
Identity: 11908
Gene: TNFRSF11A | More about : TNFRSF11A
Long gene name: TNF receptor superfamily member 11a
Synonyms gene: PDB2 LOH18CR1
Synonyms gene name: 18, NFKB activator , activator of NFKB Paget disease of bone 2 loss of heterozygosity, chromosomal region 1 tumor necrosis factor receptor superfamily, member 11a, member 11a, tumor necrosis factor receptor superfamily
Locus: 18q21, 33
Discovery year: 1998-12-04
GenBank acession: AF018253
Entrez gene record: 8792
Pubmed identfication: 9367155 10615125
Classification: CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT: OTTHUMG00000132779
Locus Specific Databases: LRG_194

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