RANK Antibody

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Catalog number: bs-7343R
Price: 263 €
Supplier: Bioss Primary Unconjugated Antibodies
Product name: RANK Antibody
Quantity: 0.1ml
Other quantities: 0.1mg 389€ 1 x 1 vial 486€ 100ug 370€
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Long name: RANK Primary Polyclonal Antibody
Also known as: RANK PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: RANK
Specificity: This is a highly specific antibody against RANK
Modification(s): None
Modification site(s): Unmodified antibody
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Subcellular location: Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RANK
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: CD265 is also expressed in dendritic cells, CD265 is widely expressed, Human and murine CD265 share 81% amino acid identity in their extracellular domains, Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of CD265, RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells, RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis, TRANCE (TNF-related activation-induced cytokines, The binding of anti-CD265 to cell surface CD265 triggers signal transduction and induces CD265 mediated bioactivity, The biological functions mediated by RANK include activation of NFkappaB and cjun N-terminal kinase, The soluble form of CD265 is able to block TRANCE induced biological activity, also known as RANK ligand, colon, enhancement of T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis, liver, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for CD265, small intestine and adrenal gland, thymus, with highest levels in skeletal muscle, CD265 is a member of the tumor necrosis factor receptor (TNFR) family
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: Activator of NFKB, CD 265, CD265, CD265 antigen, EOF, FEO, NFKB activator, ODFR, OFE, Osteoclast dferentiation factor receptor, PDB 2, RANK receptor, Receptor activator of NF KB, TNFRSF 11A, TNFSF11, TNR11_HUMAN, TRANCE R, mRANK, receptor activator of nuclear factor kappa B, TNFRSF11A
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: RANK
Short name: RANK Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: RANK (Antibody to)
Alternative technique: antibodies
Identity: 11908
Gene: TNFRSF11A | More about : TNFRSF11A
Long gene name: TNF receptor superfamily member 11a
Synonyms gene: PDB2 LOH18CR1
Synonyms gene name: 18, NFKB activator , activator of NFKB Paget disease of bone 2 loss of heterozygosity, chromosomal region 1 tumor necrosis factor receptor superfamily, member 11a, member 11a, tumor necrosis factor receptor superfamily
Synonyms: RANK CD265 FEO
Locus: 18q21, 33
Discovery year: 1998-12-04
GenBank acession: AF018253
Entrez gene record: 8792
Pubmed identfication: 9367155 10615125
Classification: CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT: OTTHUMG00000132779
Locus Specific Databases: LRG_194

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