| known also as: |
BRCT Repeat Inhibitor of TERT Expression 1, BRIT1, Hypothetical Protein FLJ12847, MCT, Microcephaly, Microcephaly Primary Autosomal Recessive 1), Anti-MCPH1 (Microcephalin 1 |
| known also as: |
BRCT Repeat Inhibitor of TERT Expression 1, BRIT1, Hypothetical Protein FLJ12847, MCT, Microcephaly, Microcephaly Primary Autosomal Recessive 1), MCPH1 (Microcephalin 1 |
| known also as: |
BRCT Repeat Inhibitor of TERT Expression 1, BRIT1, Hypothetical Protein FLJ12847, MCT, Microcephaly, Microcephaly Primary Autosomal Recessive 1), MCPH1 (Microcephalin 1 |
| known also as: |
MCPH1 |
| known also as: |
BRCT Repeat Inhibitor of TERT Expression 1, BRIT1, Hypothetical Protein FLJ12847, MCT, Microcephaly, Microcephaly Primary Autosomal Recessive 1), Anti -MCPH1 (Microcephalin 1 |
| Other names: |
BRCT-repeat inhibitor of TERT expression 1, Microcephalin, N/A, microcephalin, microcephalin 1, microcephalin isoform 3 |
| Other gene names: |
BRIT1, MCPH1, MCT, N/A, MCPH1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Other species not tested, Reactivity with mouse MCPH1 is unlikely owing to divergence of sequence between this ortholog and human MCPH1 at the site to which the epitope maps, Specific for human MCPH1 protein |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
BRCT Repeat Inhibitor of TERT Expression 1, BRIT1, Hypothetical Protein FLJ12847, MCT, Microcephaly, Microcephaly Primary Autosomal Recessive 1), MCPH1 (Microcephalin 1 |
| Short name: |
BRCT Repeat Inhibitor of TERT Expression 1, BRIT1, Hypothetical Protein FLJ12847, MCT, Microcephaly, Microcephaly Primary Autosomal Recessive 1) Antibody, MCPH1 (Microcephalin 1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BRCT Repeat suppressor on telomerase reverse transcriptase Expression 1, BRIT1, Hypothetical Protein FLJ12847, MCT, Microcephaly, Microcephaly captor Autosomal Recessive 1) (Antibody to), MCPH1 (Microcephalin 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CMM9 and DKCA2 and DKCB4 and EST2 and hEST2 and hTRT and PFBMFT1 and TCS1 and TP2 and TRT, TERT and IDBG-10998 and ENSG00000164362 and 7015, Tert and IDBG-165912 and ENSMUSG00000021611 and 21752, nuclei, telomeric RNA binding, telomeric region and cellular component this GO :0000783 and nuclear telomere cap complex and cellular component this GO :0003720 and telomerase activity and molecular function this GO :0003721 and telomeric template RNA reverse transcriptase activity and molecular function this GO :0003964 and RNA-directed DNA polymerase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005697 and telomerase holoenzyme complex and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007004 and telomere maintenance via telomerase and biological process this GO :0016605 and PML body and cellular component this GO :0022616 and DNA strand elongation and biological process this GO :0032203 and telomere formation via telomerase and biological process this GO :0042162 and telomeric DNA binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0070034 and telomeric RNA binding and molecular function this GO :0090399 and replicative senescence and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0000723 and telomere maintenance and biological process this GO :0000781 and chromosome, this GO :0003720 : telomerase activity, this GO :0003720 : telomerase activity and also this GO :0003721 : telomeric template RNA reverse transcriptase activity and also this GO :0003964 : RNA-directed DNA polymerase activity and also this GO :0005515 : protein binding and also this GO :0042162 : telomeric DNA binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046872 : metal ion binding and also this GO :0070034 : telomeric RNA binding, this GO :0003721 : telomeric template RNA reverse transcriptase activity, this GO :0003964 : RNA-directed DNA polymerase activity, this GO :0005515 : protein binding, this GO :0042162 : telomeric DNA binding, this GO :0042803 : protein homodimerization activity, this GO :0046872 : metal ion binding, this GO :0070034 : telomeric RNA binding, 60929 and IDBG-632169 and ENSBTAG00000012567 and 518884, telomerase reverse transcriptase |
| Identity: |
6954 |
| Gene: |
MCPH1 |
More about : MCPH1 |
| Long gene name: |
microcephalin 1 |
| Synonyms gene name: |
microcephaly, primary autosomal recessive 1 |
| Synonyms: |
FLJ12847 BRIT1 |
| Synonyms name: |
BRCT-repeat inhibitor of TERT expression 1 |
| Locus: |
8p23, 1 |
| Discovery year: |
1998-02-11 |
| GenBank acession: |
AK022909 |
| Entrez gene record: |
79648 |
| Pubmed identfication: |
9683597 17925396 |
| RefSeq identity: |
NM_024596 |
| Havana BLAST/BLAT: |
OTTHUMG00000163618 |