| Also known as: |
EMA / MUC1 |
| Other names: |
Breast carcinoma-associated antigen DF3, CA 15-3, CD_antigen: CD227Cleaved into the following 2 chains:Mucin-1 subunit alpha, Cancer antigen 15-3, Carcinoma-associated mucin, DF3 antigen, EMA, Episialin, H23 antigen, H23AG, KL-6, Krebs von den Lungen-6, MUC1-NT, MUC1-alpha, MUC1-betaAlternative name(s):MUC1-CT, Medullary cystic kidney disease, Mucin-1, Mucin-1 subunit beta, PEM, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin, autosomal dominant, breast carcinoma-associated antigen DF3, cancer antigen 15-3, carcinoma-associated mucin, cell surface associated, episialin, krebs von den Lungen-6, mucin 1, mucin 1, mucin-1, peanut-reactive urinary mucin, polymorphic epithelial mucin, transmembrane, tumor associated epithelial mucin, tumor-associated epithelial membrane antigen, mucin-1 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
EMA |
| Gene name synonims: |
MUC1 |
| Other gene names: |
ADMCKD, ADMCKD1, CA 15-3, CA 15-3, CD227, EMA, EMA, H23AG, KL-6, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1, MUC1-NT, MUC1-alpha, MUC1-beta, MUC1/ZD, PEM, PEM, PEMT, PUM, PUM, PUM, MUC1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
175C5 |
| Host organism: |
Mouse (Mus musculus)-Balb/c |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Theantibdy reacts with a carcinoma-associated antigen in both adenocarcinomas and squamous cellcarcinomas of different origins, This particular antibody might cross react with speacies outside of the listed ones, shows a high preference for breast carcinomas relative to normal breast epithelium |
| Purification method: |
Tissue culture supernatant |
| Form/Appearance: |
09% sodium azide |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Electron Microscopy, Flow Cytometry (FC/FACS), IHC - Frozen), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Balb/c Monoclonal [ 175C5] (IgG1) EMA / MUC1 |
| Short name: |
Mouse-Balb/c Monoclonal [clone 175C5] (IgG1) EMA / MUC1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens EMA / MUC1 (Antibody to), Mouse-Balb/c monoclonal [clonality 175C5] (IgG1) to H |
| Alternative technique: |
antibodies |
| Identity: |
7508 |
| Gene: |
MUC1 |
More about : MUC1 |
| Long gene name: |
cell surface associated , mucin 1 |
| Synonyms gene: |
PUM MCKD1 |
| Synonyms gene name: |
mucin 1, transmembrane medullary cystic kidney disease 1 (autosomal dominant) |
| Synonyms: |
CD227 PEM ADMCKD ADMCKD1 MCKD MCD |
| Locus: |
1q22 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
J05581 |
| Entrez gene record: |
4582 |
| Pubmed identfication: |
1697589 23396133 |
| RefSeq identity: |
NM_002456 |
| Classification: |
Mucins CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000035681 |