| Also known as: |
TREM-1 |
| Other names: |
Triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells 1, triggering receptor expressed on monocytes 1, triggering receptor expressed on myeloid cells 1, triggering receptor expressed on myeloid cells 1, triggering-receptor TREM1, triggering receptor expressed on myeloid cells 1 isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TREM-1 |
| Other gene names: |
CD354, TREM-1, TREM-1, TREM1, TREM1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
TREM-26 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
It is also highly expressed in inflammatory lesions caused by fungi and bacteria, It stimulates neutrophils and monocytes-mediated inflammatory responses, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TREM-1 activation, The TREM-1 pathway also plays a crucial role in septic shock, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone TREM-26 has been shown to activate monocytes and granulocytes, a receptor expressed on CD14<, amplifies the production pro-inflammatory cytokines and thus the inflammatory response, macrophages and neutrophils, monocytes, together with LPS and other PRR ligands, +<, /sup>, TREM-1 This item recognises Triggering receptor expressed on myeloid cells 1 (TREM-1), sup> |
| Form/Appearance: |
Biotin (Purified IgG conjugated to Biotin - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Western Blot (WB) |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Biotinylated |
| Gene target: |
TREM-1: |
| Short name: |
MOUSE Anti-HUMAN TREM-1: Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Biotin |
| Alternative name: |
sapiens TREM-1:biotinilated (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
17760 |
| Gene: |
TREM1 |
More about : TREM1 |
| Long gene name: |
triggering receptor expressed on myeloid cells 1 |
| Synonyms: |
TREM-1 CD354 |
| Locus: |
6p21, 1 |
| Discovery year: |
2002-08-09 |
| GenBank acession: |
AF196329 |
| Entrez gene record: |
54210 |
| Pubmed identfication: |
11922939 10799849 |
| RefSeq identity: |
NM_018643 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000014674 |