| Also known as: |
TREM-1 |
| Other names: |
N/A, Triggering receptor expressed on myeloid cells 1, triggering receptor expressed in monocytes 1, triggering receptor expressed on myeloid cells 1, triggering receptor expressed on myeloid cells 1, triggering receptor expressed on myeloid cells 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TREM-1 |
| Other gene names: |
N/A, TREM-1, Trem1, Trem1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
2A12, 3A12, L5-B8 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
, It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, Microbial infection also induces the release of soluble form of TREM-1 from monocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TREM-1 is involved in the microbial inflammatory response, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_TREM-1 mediates the septic shock pathway, a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response, which is reported to act as an inhibitor of TREM-1, TREM-1 This item recognises mouse triggering receptor expressed on myeloid cells 1 (TREM-1) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistology - Frozen (IHC), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
TREM-1 |
| Short name: |
RAT ANTI MOUSE TREM-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE TREM-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17760 |
| Gene: |
TREM1 |
More about : TREM1 |
| Long gene name: |
triggering receptor expressed on myeloid cells 1 |
| Synonyms: |
TREM-1 CD354 |
| Locus: |
6p21, 1 |
| Discovery year: |
2002-08-09 |
| GenBank acession: |
AF196329 |
| Entrez gene record: |
54210 |
| Pubmed identfication: |
11922939 10799849 |
| RefSeq identity: |
NM_018643 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000014674 |