| known also as: |
Anti-RABBIT ANTI HUMAN PAI-1:Biotin |
| known also as: |
RABBIT ANTI HUMAN PAI-1:Biotin |
| known also as: |
Lapin ANTI Homo sapiens PAI-1:Biotin |
| known also as: |
PAI-1 |
| Other names: |
Endothelial plasminogen activator inhibitor, Plasminogen activator inhibitor 1, Serpin E1, clade E (nexin, clade E (nexin, endothelial plasminogen activator inhibitor, member 1, member 1, plasminogen activator inhibitor 1, plasminogen activator inhibitor type 1), plasminogen activator inhibitor type 1), serine (or cysteine) proteinase inhibitor, serpin E1, serpin peptidase inhibitor, plasminogen activator inhibitor 1 |
| Gene name: |
PAI-1 |
| Other gene names: |
PAI, PAI, PAI-1, PAI-1, PAI1, PAI1, PLANH1, PLANH1, SERPINE1, SERPINE1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
_x000D__x000D_Increased levels of PAI-1 are associated with diabetes, a 45kDa serine protease inhibitor and member of the serpin family, and can be induced by obesity related factors including insulin, and hence fibrinolysis, cardiovascular disease and an increased occurrence of thrombosis in obesity, glucose and VLDL (very-low-density lipoprotein), otherwise known as SERPINE1, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), PAI-1 This item specifically recognises human PAI-1 (plasminogen activator inhibitor-1) |
| Form/Appearance: |
Biotin (Purified IgG conjugated to Biotin - lyophilised) |
| Concentration: |
1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase |
| Conjugation: |
Biotinylated |
| Gene: |
Elevated PAI-1 is a risk factor for , (PAI-1) also known as , Plasminogen activator inhibitor-1 , SERPINE1 , and , atherosclerosis, endothelial plasminogen activator inhibitor , gene, is a , or , protein , serpin E1 , that in humans is encoded by the , thrombosis |
More about : Elevated PAI-1 is a risk factor for , (PAI-1) also known as , Plasminogen activator inhibitor-1 , SERPINE1 , and , atherosclerosis, endothelial plasminogen activator inhibitor , gene, is a , or , protein , serpin E1 , that in humans is encoded by the , thrombosis |
| Gene target: |
PAI-1: |
| Short name: |
Anti-HUMAN PAI-1: |
| Label: |
Biotin |
| Alternative name: |
sapiens PAI-1:biotinilated, antibody to-H |