| Also known as: |
CD51 |
| Other names: |
Integrin alpha-V, Vitronectin receptor subunit alpha, alphav-integrin, integrin alpha V, integrin alpha-V, vitronectin receptor alpha polypeptide (VNRA), vitronectin receptor subunit alpha, integrin alpha-V |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD51 |
| Other gene names: |
1110004F14Rik, 2610028E01Rik, CD51, D430040G12Rik, Itgav, N/A, Itgav |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
RMV-7 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Alpha-V integrins may play a role in embryo implantation, CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61, CD51/CD61 is primarily expressed on myeloid cells and activated T-cells, Heterodimers of CD51/CD61 function as a receptor for vitronectin, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, This particular antibody might cross react with speacies outside of the listed ones, a 140 kD alpha subunit of the vitronectin receptor, and CD31 in some cell types, and a wide array of RGD-containing proteins including fibronectin, angiogenesis and wound healing, as well as blocking LAK cell cytotoxicity, fibrinogen, fibronectin, laminin, thrombospondin and osteopontin, von Willebrand factor, which is otherwise known as the integrin alpha v chain, CD51 This item recognises murine CD51 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD51 |
| Short name: |
RAT ANTI MOUSE CD51 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD51 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6150 |
| Gene: |
ITGAV |
More about : ITGAV |
| Long gene name: |
integrin subunit alpha V |
| Synonyms gene: |
VNRA MSK8 VTNR |
| Synonyms gene name: |
alpha V , alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) integrin, antigen identified by monoclonal antibody L230 vitronectin receptor integrin |
| Synonyms: |
CD51 |
| Locus: |
2q32, 1 |
| Discovery year: |
1988-07-19 |
| Entrez gene record: |
3685 |
| Pubmed identfication: |
2454952 |
| RefSeq identity: |
NM_002210 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000132635 |